Aiden Flynn, BSc MSc PhD
Aiden is the founder of Exploristics and has more than 20 years’ experience in drug discovery and clinical development.
After seven years as a lecturer at University College, London, he spent ten years at GlaxoSmithKline as a director of statistical support for biomarker studies across research and development.
He was responsible for developing and implementing the pharmacogenetics strategy that enabled the use of genetics data in clinical studies. This involved the integration of a wide range of capabilities across R&D such as new analysis tools and methods, bioinformatics, data standards, processes and training.
In recent years, Aiden has worked closely with regulatory authorities, such as the FDA and EMEA, to develop tools and guidelines that support the use of biomarkers in clinical studies. Since founding Exploristics in 2009, Aiden has proven to be an innovative CEO, attracting over 50% of the world’s top pharmaceutical companies as clients as well as many biotechnology, device and diagnostic companies.
With 100% of all clients retained and repeat business a valid marker of quality, the company continues its successful track record.
Anne-Marie Duggan, BSc
Anne-Marie is an experienced statistician with a Masters in Clinical Trials, a Bachelors in Mathematics, Statistics and Operational Research and over 10 years’ in the pharmaceutical industry with particular expertise in the application of statistics in drug discovery and development, working to GLP/GCP standards for regulatory submissions.
As Head of Services, Anne-Marie oversees the Statistics and Statistical Programming teams within Exploristics. In her 4 years as a senior staff member in Exploristics she has supported the varied clinical studies undertaken including safety, efficacy and oncology clinical trials, epidemiology, health outcomes and economics, medical devices and diagnostic studies involving biomarker analysis and prediction of disease.
John McGrann, BSc MSc
John has over 35 years’ experience leading change and growth in multiple roles the IT and Services sectors.
Following his graduation John worked in the IT sector delivering solutions to major customers in both the public and private sector, before moving into Business Development and Management roles where much of his focus was in the retail, health and government sectors. Moving into the services sector John took up a role as IT and General Manager for a multi-national food processor supporting the rapid expansion and growth of the business.
Following this John founded, grew and sold his own Software Development business providing innovative food security and traceability software as well as IT services to the health sector.
More recently John has played leadership roles growing the presence of US based IT and services companies in the UK and Europe delivering services in the finance, pharmaceutical and government sectors.
John is recognised for his commitment to delivery of quality services to customers.
Frances Denny, BSc PhD
Frances has over thirteen years’ experience in statistical modelling the clinical and pharmaceutical arenas.
Frances obtained a BSc Honours in Mathematics and a PhD in Statistics from Queen’s University Belfast with a primary research area in the assessment of modelling techniques for patient reported outcomes.
Originally joining Exploristics as a principal statistician in 2009, Frances has utilised her strong management and technical skills to implement new processes for project delivery across various therapeutic areas and study types. Frances is now the CAO, responsible for business operations.
Sam Miller, BA MSc
Sam has 19 years’ experience as a statistician in the pharmaceutical industry, since graduating with a BA in Mathematics from the University of Cambridge and an MSc in Statistics from University College, London.
Prior to joining Exploristics in 2017, Sam spent many years at GlaxoSmithKline where he gained in-depth experience of the Pharmaceutical sector providing statistical support to clinical trials at all stages of discovery and development. This included everything from FTIH studies through proof of concept and dose-ranging trials to pivotal studies supporting regulatory submission, as well as statistical input to portfolio-level decision-making across multiple drug projects.
Sam’s areas of technical expertise include Experimental Medicine, adaptive designs and applications of Bayesian approaches to clinical trial design and analysis. He is enthusiastic about the application of any methods to make earlier, better- informed decisions about the development path for potential new medicines.
This requires innovative and flexible thinking around the statistical approach, together with strong communication and influencing skills. Sam has co-authored over 50 articles in medical and statistical publications including The Lancet and Journal of Biopharmaceutical Statistics.
Bernard North, BSc MSc (Eng) PhD
Bernard is a highly skilled Statistician with over 20 years’ experience working in clinical research. With a PhD in Statistics from the University of Reading, Bernard has worked widely in medical statistics for clinical trials in research areas including diabetes, genetics and oncology.
Before joining Exploristics in July 2016, Bernard worked at the Centre for Cancer Prevention at Queen Mary, University of London, focusing on several clinical trials associated with cancer prevention, including prostate cancer where he identified novel biomarkers for the risk stratification of prostate cancer patients to detect individuals requiring more aggressive therapy.
As a Statistical Consultant and Applications Specialist at Exploristics, Bernard advises on and delivers study analysis and design options for clients, providing key statistical support for both the Biostatistics Services and Software Development teams.