The team at Exploristics has an extensive publication record, with a selection of relevant examples listed below
Speciality Statistics

Kivitz, A. et al., Phase 2 Dose-Finding Study in Patients with Gout using SEL-212, a Novel PEGylated Uricase (SEL-037) Combined with Tolerogenic Nanoparticles (SEL-110). Rheumatol. Ther. 2023. In press. View

Gaughan, E. et al., An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis (DEFINE): A Phase Ib/IIa Randomised Controlled Trial. Am. J. Respir. Crit. Care Med. 2022. In press. View

Hirani, N. et al., Target-inhibition of Gelectin-3 by Inhaled TD139 in Patients with Idiopathic Pulmonary Fibrosis. European Respiratory Journal 2020; 57 (3). In press. View

DeVincenzo, J. et al., Safety and Anti-viral Effects of Nebulized PC786 in a Respiratory Syncytial Virus Challenge Study. Journal of Infectious Diseases 2020. In press. View

Win, T. et al., Pulmonary 18F-FDG uptake helps refine current risk stratification in idiopathic pulmonary fibrosis (IPF). Eur J Nucl Med Mol I 2018; 45:806-15. View

Maher, T. M. et al., An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study. Lancet Respir Med 2017; 5: 946-55. View

Meta-analysis on cardiovascular disease. View

Watson, L. et al., Cart analysis as a tool to determine optimal treatment intensification time in diabetes. Value in Health 2015 11;18(7): A682. View

Jenkins, R. G. et al., Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective multicentre PROFILE study.  Lancet Respir Med 2015; 3: 6: 462-472. View

Alderton, W. et al., CA19.9 Profiles in Samples Predating Pancreatic Cancer Diagnosis – a Nested Case Control Study in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). View

International Survey on Diabetic Retinopathy. View

Precision Medicine

Flynn, A. et al., Advances in Predictive, Preventive and Personalised Medicine. 2015 Vol 9 – Preventive and Predictive Genetics: Towards Personalised Medicine. Editors: Godfrey Grech and Iris Grossman ISBN: 978-3-319-15343-8 (Print) 978-3-319-15344-5.

Olazarán et al. A Blood-Based, 7-Metabolite Signature for the Early Diagnosis of Alzheimer’s Disease. J Alzheimer’s Dis 2015; 45 (4): 1157–73. View

Exploristics profile in Personalized Medicine 2015; 12 (6), 537-40. View

Flynn, A. Pharmacogenetics: practices and opportunities for study design and data analysis. Drug Discov Today 2011; 16 (19-20): 862-6. View

Trusheim, M. et al., Quantifying factors for the success of stratified medicine. Nat Rev Drug Discov 2011; 10, 817-833. View

Jenkins, M., et al., A statistician’s perspective on biomarkers in drug development. Pharm Stat 2011; 10 (6): 494-507. View

Epidemiology and Real World

Chrystyn, H., et al., Device errors in asthma and COPD: systematic literature review and meta-analysis. NPJ Prim Care Respir Med 2017; 27 (1):22. View

Watson, L., et al., Consequences of delaying treatment intensification in type 2 diabetes: evidence from a UK database. Curr Med Res Opin 2016; 32(9), 1465-75. View

Bushe, C. et al., Understanding the treatment of adult Attention Deficit Hyperactivity Disorder patients in general practice: A United Kingdom Database Study. Pragmatic and Observational Research 2015; 6: 1-12. View

Amber, V. et al., A database analysis of patients eligible for second-line lipid-lowering treatment for hypercholesterolaemia in England. Value in Health. 2014. 17(7): A476-A477. View

Other Relevant Capabilities

Beatty, S. et al., Secondary Outcomes in a Clinical Trial of Carotenoids with Coantioxidants Versus Placebo in Early Age-Related Macular Degeneration. Ophthalmol 2013; 120 (3): 600-606. View

Denny, F. et al., Rasch Analysis of the Daily Living Tasks Dependent on Vision (DLTV). Invest Ophthamol Vis Sci 2007; 48:1976-82. View

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