Build. Simulate. Analyse. Optimise. Visualise.

KerusCloud is a uniquely powerful revolutionary cloud-based study simulation platform that allows clinical development teams to explore multiple study design and analysis options in a virtual environment. Its use supports earlier data-driven design decisions to ensure that clinical studies are fully optimised statistically from the outset to maximise their chances of success.

Build:

Integrate existing and emerging knowledge and data sources from the literature, clinical trial data, real-world data and expert opinion to build realistic synthetic patient populations.

Simulate:

Sample these virtual populations to generate highly realistic study simulations in minutes for high numbers of scenarios.

Analyse:

Explore multiple fixed and adaptive study designs, analysis and decision-making strategies by applying different statistical analyses and decision criteria.

Optimise:

Evaluate the suitability of different trial designs and data analysis methods guided by the quantified POS for each approach.

Visualise:

View and share simulated outcomes with Probability of Success values using the interactive heatmap to quickly identify the design and analysis strategy most likely to deliver success.

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Build. Simulate. Analyse. Optimise. Visualise.

KerusCloud is a uniquely powerful revolutionary cloud-based study simulation platform that allows clinical development teams to explore multiple study design and analysis options in a virtual environment. Its use supports earlier data-driven design decisions to ensure that clinical studies are fully optimised statistically from the outset to maximise their chances of success.

Build. Integrate existing and emerging knowledge and data sources, including publications, clinical trial data, real-world data and expert opinion to build realistic virtual patient populations.

Simulate. Sample the virtual populations you build to generate realistic simulations in minutes for thousands of study scenarios.

Analyse. Explore multiple study design, analysis and decision-making strategies by applying different statistical analyses and decision criteria.

Optimise. Quantatively assess the suitability of differing trial designs and data analysis methods, calculating the probability of success for each approach.

Visualise. View simulated outcome results in minutes via an interactive heatmap to quickly identify the strategy most likely to be successful.

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01 | Generate Realistic Patient Populations

Create synthetic datasets for highly realistic virtual patient populations by extracting information as real world data or by pre-existing data models.

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02 | Build study scenarios

Construct parallel development scenarios using virtual patient populations following intuitive workflows.

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03 | Cloud-based simulation

Select from a range of fixed and adaptive study designs as well as different statistical analysis options before running high numbers of complex study simulations in parallel in minutes using the intensive processing power of the cloud.

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04 | Interactive visualisation of results

View, explore and share simulated scenario results to understand the interactions between multiple study parameters and their effect on outcomes.

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05 | Identify the best design for real studies

Review results to select the optimal design and analysis options for real studies so they can answer relevant clinical questions, first time.

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06 | Export Simulated Data

Export detailed reports containing simulated virtual populations, study designs, analyses and decision criteria for further exploration, validation or audit.

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“The simulations were beautiful. They exploited the full potential of a historical data set to inform the design of our study. Options were ruled in or out and critical elements identified. This allowed us to simplify, enhance and de-risk the study design.”

Chief Medical Officer Small BioTech UK

“We were extremely pleased with the results of the work. Until Exploristics became involved we were struggling to come to conclusions about the utility of the biomarkers being evaluated. The results with Kerus provided our team with a solid understanding of the data allowing clear conclusions to be drawn.”

Senior Scientific Director, Respiratory TAU, GSK

The Kerus simulation tool is very powerful! The simulations for our pivotal trials showed us a suitable and straight forward path to reach marketing approval with a smaller number of patients and quicker compared to our original plans. Discussions with statistic experts from CROs, investigators and key opinion leaders confirmed the approach.

CEO, Small Biotech Germany