Statistical Insights

Plague, problems and profiting from failure
Plague, problems and profiting from failure 558 344 Exploristics

By Kimberley Hacquoil, Exploristics CDSO

 

I recently attended the Statisticians in the Pharmaceutical Industry (PSI) flagship annual conference which had many fantastic presentations and sessions. I was reflecting on a couple of themes which resonated for me in my …

Good games and mighty models

Good games and mighty models
Good games and mighty models 558 344 Exploristics

By Kimberley Hacquoil, Exploristics CDSO

During a 3-day conference, statisticians, programmers and data scientists within the pharmaceutical industry were invited to play their cards right on Exploristics’ bespoke app which was built in-house. With the chance of becoming the daily …

I’ve got the power – or have I?

I’ve got the power – or have I?
I’ve got the power – or have I? 558 344 Exploristics

By Exploristics CDSO, Kim Hacquoil

Aiming for 80% or 90% power for a clinical study is standard practice, however, it is possible that using power as a proxy for probability of success for decision-making is partly to blame for the …

Unlocking valuable insights from the virtual world

Unlocking valuable insights from the virtual world
Unlocking valuable insights from the virtual world 558 344 Exploristics

By Exploristics CDSO, Kim Hacquoil

Simulation is the act or process of imitating the functioning or behaviour of a real-world system or process by means of another system or process, usually a computer program. While it has been successfully incorporated …

From cars to clinical trials: how simulation can improve design

From cars to clinical trials: how simulation can improve design
From cars to clinical trials: how simulation can improve design 558 344 Exploristics

By Exploristics CDSO, Kim Hacquoil

For many years the car industry has been improving the safety of the cars it builds through rigorous testing using crash test dummies. Data collected from these dummies have led to the inclusion of key …

One size does not fit all

One size does not fit all
One size does not fit all 558 344 Exploristics

By Exploristics CDSO, Kim Hacquoil

The aim of drug development is to get an effective and safe drug to market to help patients. However, the definition of a successful drug development “program” is dependent on more than just regulatory success. …

Shifting the development paradigm with innovative trial design

Shifting the development paradigm with innovative trial design
Shifting the development paradigm with innovative trial design 558 344 Exploristics

By Exploristics CEO, Aiden Flynn

Pandemic successes like the RECOVERY trial have provided the pharmaceutical industry with a glimpse of how innovative trial design could shake up historic approaches to clinical development to drive greater efficiency. They have reignited interest …

Birth of data science team

Birth of the Data Science Team at Exploristics
Birth of the Data Science Team at Exploristics 558 344 Exploristics

By Exploristics CDSO, Kimberley Hacquoil

From the outset, Exploristics have embedded innovation into the fabric and culture of the company. Indeed, we invest more than one third of our revenue every year in research and development of new technology and …

Disparate and Desperate – curse of the diminishing N

Disparate and Desperate – curse of the diminishing N
Disparate and Desperate – curse of the diminishing N 558 344 Exploristics

By Exploristics CDSO, Kimberley Hacquoil

There are pressures for the pharmaceutical industry to utilise novel and innovative methods to incorporate historical data and real-world evidence into the design and analysis of clinical trials. The objectives of doing this is to …

Are external control arms worth the extra effort?

Are external control arms worth the extra effort?
Are external control arms worth the extra effort? 558 344 Exploristics

By Exploristics CDSO, Kimberley Hacquoil

The FDA have recently published a draft guidance for the design and conduct of externally controlled trials which specifically focuses on the use of patient level data as a full external control arm. This external …

what can we find for you?

We are thrilled to announce that Exploristics is now part of MMS, a global data-focused CRO!

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