kerus case studies

Biomarker Evaluation

Biomarker Evaluation 558 344 Exploristics
Case Study: Establishing biomarkers of treatment efficacy in liver disease

 

The Challenge

A privately held biotechnology company at an early stage of clinical development was interested in designing a study using biomarkers to indicate treatment efficacy in subjects with

KerusCloud Supporting Go:No Go Decision-Making Criteria for Early Stage Studies

Go/No Go Decision-Making

Go/No Go Decision-Making 558 344 Exploristics
Case Study: Creating Go/No Go Decision-Making
Criteria for Early Stage Studies.

 

The Challenge

A privately held biotechnology company was developing a novel therapeutic targeting fibrosis and inflammation.Following completion of a successful first-in-human Phase I study evaluating the investigative agent

KerusCloud Defining Endpoints

Best Endpoint

Best Endpoint 558 344 Exploristics
Case Study: Identifying the most efficient way to generate clinical evidence given multiple uncertainties

 

KerusCloud is a ground-breaking new clinical study design and analytics software platform which delivers smarter real-time studies for today’s clinical research challenges.

Using powerful cloud-based …

KerusCloud Effective Precision Medicine Strategies

Precision Medicine

Precision Medicine 558 344 Exploristics
Case Study: Effective precision medicine strategies with KerusCloud.

 

Over 90% of treatments undergoing trials currently fail to reach the market. Effective study planning and analysis is essential to reduce these failure rates and maximise the chances of a successful

KerusCloud Real World Evidence

Real World Evidence

Real World Evidence 558 344 Exploristics
Case Study: Simulating patient level outcome data to inform clinical trial design based on RWE, clinical trial and literature data.

 

KerusCloud is a ground-breaking new clinical study design and analytics software platform which delivers smarter real-time studies for today’s …

KerusCloud Bayesian Extrapolation

Bayesian Extrapolation

Bayesian Extrapolation 558 344 Exploristics
Case Study:  Bayesian extrapolation to evaluate efficacy in pediatric subjects using adult data.

 

KerusCloud is a ground-breaking new clinical study design and analytics software platform which can generate and evaluate the performance and outcomes of clinical development
scenarios. In …

KerusCloud Composite Biomarker

Composite Biomarker

Composite Biomarker 558 344 Exploristics
Case Study: Building and validating a composite biomarker model to predict emphysema progression

 

KerusCloud is a ground-breaking new clinical study design and analytics software platform which delivers smarter real-time studies for today’s clinical research challenges.

Using powerful cloud-based processing, …

KerusCloud Identifying Best Strategy

Identifying Best Strategy

Identifying Best Strategy 558 344 Exploristics
Case Study: Identifying the best overall strategy for study designs and drug development pathways

 

KerusCloud is a ground-breaking new clinical study design and analytics software platform which delivers smarter real-time studies for today’s clinical research challenges.

Using powerful cloud-based …

KerusCloud Enabling Early Approval

Enabling Early Approval

Enabling Early Approval 558 344 Exploristics
Case Study: Enabling early approval through a smarter approach to generating robust clinical evidence

 

KerusCloud is a ground-breaking new clinical study design and analytics software platform which delivers smarter real-time studies for today’s clinical research challenges.

Using powerful cloud-based …