Statistical Insights
Counting the Costs of Clinical Trials: Why Rethinking Trial Design Matters
Clinical development is extremely costly, in terms of money, time and patient burden.
Estimands – The “what” and the “how” of drug discovery
In clinical development, clear, precise and transparent specification of the research question and associated treatment effects of interest are vital.
Embedding New Technologies into Clinical Studies
Recently, I attended the IoT Clinical Trials Europe conference on integrating IoT (the internet of things) and emerging technologies to optimise clinical trials and patient outcomes.
Developments in Digital Data
When I first started working in the pharmaceutical industry, most clinical trials used paper case report forms (CRF) to collect information from patients.
Why Simulation is Needed to Optimise Both Adaptive & Fixed Clinical Trial Designs
Simulation is an invaluable tool for evaluating and mitigating the risks of clinical trials before conducting the studies in real time
Smarter Clinical Trial Design using Study Simulation Can Address Recruitment Challenges
With recruitment often a key barrier to study success, discover how smarter trial design using study simulation can help to relieve this
Drug Repurposing and Real-World Data: Lessons from COVID-19
How the pandemic has heightened interest in unlocking the value of RWD.
Designing clinical studies for success and not failure
Why aren’t biostatisticians involved earlier in the clinical trial design process?
Going Synthetic with Real-World Data
Real-world data has the potential to have a positive impact on the treatment of serious conditions, providing much-needed insights into the health and treatment of patients in an everyday setting…
The liberation of real-world data
The costs and complexities associated with drug development are fuelling the drive for more efficient healthcare delivery…
Belfast is where Exploristics’ heart is
Why Belfast is a great place to set up a life science business.
Why Getting Smaller Doesn’t Mean Thinking Smaller
In the wake of a tumultuous 2020, I have taken the opportunity to reflect on the progress Exploristics has made as a company and reappraise my reasons for setting it up.
Clinical trials after COVID-19
The challenges faced by the Pharmaceutical Industry have been well documented…
COVID-19: Where there’s a will there’s a way
The COVID-19 pandemic has demonstrated the importance of science and the dedication of scientists in overcoming the challenges that we face…
Interviews
The Effective Statistician
Exploristics CEO, Aiden Flynn, joins Alexander Schacht on his Effective Statistician podcast to discuss the power of simulation in designing clinical studies.
Common Causes of Clinical Trial Failures
A discussion with Matthew Cardinal from Halloran Consulting Group.
People Always, Patients Sometimes
Exploristics’ CEO discusses how data simulation studies can reduce the risk and costs of clinical trials.
Webinars
KerusCloud Webinar July 2021: smarter clinical study design and analysis approaches using simulation
Most clinical trials fail, but simulations are revolutionising study design to improve success rates. Get ahead of the curve to learn more about this game changing approach!
Counting the Costs of Clinical Trials: Why Rethinking Trial Design Matters
Clinical development is extremely costly, in terms of money, time and patient burden.
Estimands – The “what” and the “how” of drug discovery
In clinical development, clear, precise and transparent specification of the research question and associated treatment effects of interest are vital.
Embedding New Technologies into Clinical Studies
Recently, I attended the IoT Clinical Trials Europe conference on integrating IoT (the internet of things) and emerging technologies to optimise clinical trials and patient outcomes.
Developments in Digital Data
When I first started working in the pharmaceutical industry, most clinical trials used paper case report forms (CRF) to collect information from patients.
Why Simulation is Needed to Optimise Both Adaptive & Fixed Clinical Trial Designs
Simulation is an invaluable tool for evaluating and mitigating the risks of clinical trials before conducting the studies in real time
Smarter Clinical Trial Design using Study Simulation Can Address Recruitment Challenges
With recruitment often a key barrier to study success, discover how smarter trial design using study simulation can help to relieve this
Drug Repurposing and Real-World Data: Lessons from COVID-19
How the pandemic has heightened interest in unlocking the value of RWD.
Designing clinical studies for success and not failure
Why aren’t biostatisticians involved earlier in the clinical trial design process?
Going Synthetic with Real-World Data
Real-world data has the potential to have a positive impact on the treatment of serious conditions, providing much-needed insights into the health and treatment of patients in an everyday setting…
The liberation of real-world data
The costs and complexities associated with drug development are fuelling the drive for more efficient healthcare delivery…
Belfast is where Exploristics’ heart is
Why Belfast is a great place to set up a life science business.
Why Getting Smaller Doesn’t Mean Thinking Smaller
In the wake of a tumultuous 2020, I have taken the opportunity to reflect on the progress Exploristics has made as a company and reappraise my reasons for setting it up.
Clinical trials after COVID-19
The challenges faced by the Pharmaceutical Industry have been well documented…
COVID-19: Where there’s a will there’s a way
The COVID-19 pandemic has demonstrated the importance of science and the dedication of scientists in overcoming the challenges that we face…
Interviews
The Effective Statistician
Exploristics CEO, Aiden Flynn, joins Alexander Schacht on his Effective Statistician podcast to discuss the power of simulation in designing clinical studies.
Common Causes of Clinical Trial Failures
A discussion with Matthew Cardinal from Halloran Consulting Group.
People Always, Patients Sometimes
Exploristics’ CEO discusses how data simulation studies can reduce the risk and costs of clinical trials.
Webinars
KerusCloud Webinar July 2021: smarter clinical study design and analysis approaches using simulation
Most clinical trials fail, but simulations are revolutionising study design to improve success rates. Get ahead of the curve to learn more about this game changing approach!
White Papers
White Papers
Better Adherence, Higher Engagement:
Finding The Clinical Trials Sweet Spot
Clinical trial sponsors and clinical research organizations must work through an ever-expanding set of challenges to ensure their studies of new drugs produce valid results. And they must do so while strictly managing costs and timelines. As more trials make use of inhome settings, digital technologies and realtime patient data, the pressure increases to efficiently manage a process that’s dramatically different from the traditional methods of direct observation inside the walls of a clinic.
Engaging With Regulators On Novel Statistical Approaches To Clinical Development
The Pharmaceutical Industry is undergoing significant change as it faces extreme pressure to deliver new treatments to market at a time of increased spending in R&D. Multiple economic pressures are being exerted on the industry, ranging from an impending patent cliff, a decrease in income due to greater competition from generics and biosimilars, to demands on drug pricing by governments.
Want to find out more? Get in touch.